Oral Pigmentation as a Sign of Addison’s Disease: A Brief Reappraisal

Pigmented lesions are frequently found in the oral cavity. Their overlapping clinical features should prompt the physician to carefully evaluate the patient’s medical history for a differential diagnosis. Oral pigmentations may represent physiological changes or be a manifestation of more serious diseases. Here, we describe a patient who was affected by brown maculae involving the perioral region and oral cavity. The diagnostic challenge of Addison’s disease along with a brief review on the topic is then presented.